16 results (0,57345 seconds)

Brand

Merchant

Price (EUR)

Reset filter

Products
From
Shops

Bench to Bedside Diagnostic Microbiology for the Clinicians

Geriatric Rehabilitation From Bedside to Curbside

Translational Medicine Strategies and Statistical Methods

Translational Medicine Strategies and Statistical Methods

Examines Critical Decisions for Transitioning Lab Science to a Clinical SettingThe development of therapeutic pharmaceutical compounds is becoming more expensive and the success rates for getting such treatments approved for marketing and to the patients is decreasing. As a result translational medicine (TM) is becoming increasingly important in the healthcare industry – a means of maximizing the consideration and use of information collected as compounds transition from initial lab discovery through pre-clinical testing early clinical trials and late confirmatory studies that lead to regulatory approval of drug release to patients. Translational Medicine: Strategies and Statistical Methods suggests a process for transitioning from the initial lab discovery to the patient’s bedside with minimal disconnect and offers a comprehensive review of statistical design and methodology commonly employed in this bench-to-bedside research. Documents Alternative Research Approaches for Faster and More Accurate Data Judgment CallsElaborating on how to introduce TM into clinical studies this authoritative work presents a keen approach to building executing and validating statistical models that consider data from various phases of development. It also delineates a truly translational example to help bolster understanding of discussed concepts. This comprehensive guide effectively demonstrates how to overcome obstacles related to successful TM practice. It contains invaluable information for pharmaceutical scientists research executives clinicians and biostatisticians looking to expedite successful implementation of this important process. | Translational Medicine Strategies and Statistical Methods

GBP 59.99
1

Point of Care Ultrasound Made Easy

Basic Transesophageal and Critical Care Ultrasound

Basic Transesophageal and Critical Care Ultrasound

Basic Transesophageal and Critical Care Ultrasound provides an overview of transesophageal ultrasound of the heart lung and upper abdomen as well as basic ultrasound of the brain lung heart abdomen and vascular system. Ultrasound-guided procedures commonly used in critically ill patients are also covered. With more than 400 clinical images this well-illustrated text and its accompanying videos demonstrate new developments and challenges for those interested in mastering basic transesophageal echocardiography (TEE) and bedside surface ultrasound. Each chapter is presented in an easy-to-read format that includes color diagrams and ultrasound images which optimize interactive learning for both novice and experienced clinicians. The book is divided into two parts. The first is dedicated to basic TEE while the second provides focused coverage of bedside ultrasound. The book also includes chapters on extra-cardiac TEE and ultrasound of the brain—unconventional areas that will become more important in the future as clinicians evaluate not only the etiology of hemodynamic instability but also the impact on multiple organs and systems such as the kidney liver splanchnic perfusion and brain. This text is an invaluable resource to those preparing for the National Board of Echocardiography’s Examination of Special Competence in Basic Perioperative Transesophageal Echocardiography (PTEeXAM) and its equivalents outside the USA and Canada. In addition it prepares physicians for the American College of Chest Physician’s critical care ultrasound certification. The contents follow the syllabus of the TEE basic echo exam to ensure complete coverage of a trainee's requirements. It also includes sample questions and two helpful mock exams. Written by a multidisciplinary team of experts in TEE the book is a must-have for those in training and in practice.

GBP 170.00
1

Gamma Cameras for Interventional and Intraoperative Imaging

Imaging in Critical Care Medicine

The Beginner's Guide to Intensive Care A Handbook for Junior Doctors and Allied Professionals

Intensive Care Nursing A Framework for Practice

Principles and Applications of Therapeutic Ultrasound in Healthcare

Principles and Applications of Therapeutic Ultrasound in Healthcare

Principles and Applications of Therapeutic Ultrasound in Healthcare introduces concepts principles construction and applications of therapeutic ultrasound: from bench to bedside. A comprehensive examination of the industry and medical application of ultrasound therapy this book highlights working principles research progress and system structures of therapeutic ultrasound. It describes the principles of therapeutic ultrasound details the system construction introduces current and emerging applications and discusses developing therapeutic ultrasound technologies. Divided into two parts the book first introduces the fundamentals of biomedical acoustics discusses ultrasound calibration methods and the structures of available therapeutic ultrasound systems before moving on to the various applications of ultrasound therapy used in clinics. It includes a variety of extensive clinical trials outcome photos and illustrating figures and a critical commentary on the challenges in this field. The author discusses topics that include:The derivation of wave equationThe mathematical solution of the wave propagationThe phenomena of reflectionRefraction and transmission in the acoustic field from different acoustic sourcesThe radiation pattern of the ultrasound transducerThe acoustical properties of biological tissuesUltrasound-induced bioeffectsCavitationThe design of the ultrasound transducerThe characterization method of the produced acoustic fieldAn easy reference offering full coverage of popular ultrasound therapies Principles and Applications of Therapeutic Ultrasound in Healthcare provides a simple explanation of fundamental acoustics including wave equation propagation nonlinearity and transducer design. It also discusses other potential applications and is geared toward academia industry and researchers.

GBP 38.99
1

Epilepsy Mechanisms Models and Translational Perspectives

Epilepsy Mechanisms Models and Translational Perspectives

Epilepsy has afflicted humankind throughout recorded history; yet it is only in the last half-century that significant progress has been made in our basic understanding of the epileptic brain. Pivotal advances in drug development and surgical techniques as well as the emergence of innovative approaches such as electrical stimulation of the nervous system have led to a substantial reduction in the morbidity and mortality of patients with epilepsy. At the same time remarkable developments in neuroscience have enhanced our understanding of brain structure and function. Epilepsy: Mechanisms Models and Translational Perspectives incorporates new translational advances that bring epilepsy therapies from the laboratory bench to the bedside and back again. It brings together the work of more than 70 of the field’s most respected and cutting-edge researchers and clinicians. In 24 chapters this extraordinarily comprehensive and current work:Offers an overview of the basic anatomic and functional substrates of seizure genesis and considers novel pathogenic concepts that have both emerged and been validated experimentallyExamines antiepileptic drug therapy including the latest on molecular targets Looks at the state of surgical treatments for epilepsy and discusses advances in the fields of structural and functional neuroimaging Reviews the variety of nontraditional therapeutic options such as the ketogenic diet the vagus nerve stimulator immunomodulators neurosteroids herbs and botanicals Investigates neuroendocrine hormonal and biobehavioral factors that influence seizure susceptibility—information that can be incorporated into the design of treatment algorithms on an individualized basis Provides a glimpse of what future epilepsy therapies might look like from novel mechanisms of drug delivery to gene and stem-cell therapies for epilepsy to seizure detection meth | Epilepsy Mechanisms Models and Translational Perspectives

GBP 59.99
1

Biologics and Biosimilars Drug Discovery and Clinical Applications

Biologics and Biosimilars Drug Discovery and Clinical Applications

Biologics and Biosimilars: Drug Discovery and Clinical Applications is a systematic integration and evaluation of all aspects of biologics and biosimilars encompassing research and development clinical use global regulation and more. Biosimilars are biological therapeutic agents designed to imitate a reference biologic with high similarities in structure efficacy and safety but also with potential clinical effective and cost-efficient options for the manufacturers payers clinicians and patients. Most of the top-selling prescription drugs in the current market are biologics which have revolutionized the treatment strategies and modalities for life-threatening and/or rare diseases. This book outlines the key processes and challenges in drug development regulations and clinical applications of biologics biosimilars and even interchangeable biosimilars. Global experts in the field discuss essential categories and prototype drugs of biologics and biosimilars in clinical practice such as allergenics blood and blood components cell treatment gene therapy recombinant therapeutic proteins or peptides tissues and vaccines. Additional features: Integrates the latest bench and bedside evidence of drug development and regulations of biologics and biosimilars Contains key study questions for each chapter to guide the readers as well as drug charts for all therapeutic applications of biologics and biosimilars Presents detailed schematic illustrations to explain the drug development clinical trials regulations and clinical applications of biologics and biosimilars This book is an invaluable tool for health care professional students providers and pharmaceutical and health care industries as well as the public providing readers with educational updates about the drug development and clinical affairs of biological medications and their similar drugs. | Biologics and Biosimilars Drug Discovery and Clinical Applications

GBP 130.00
1

The Voices and Rooms of European Bioethics

The Voices and Rooms of European Bioethics

This book reflects on the many contributions made in and to European bioethics to date in various locations and from various disciplinary perspectives. In so doing the book advances understanding of the academic and social status of European bioethics as it is being supported and practiced by various disciplines such as philosophy law medicine and the social sciences applied to a wide range of areas. The European focus offers a valuable counter-balance to an often prominent US understanding of bioethics. The volume is split into four parts. The first contains reflection on bioethics in the past present and future and also considers how comparison between countries and disciplines can enrich bioethical discourse. The second looks at bioethics in particular locations and contexts including: policy boardrooms and courtrooms; studios and virtual rooms; and society while the third part explores the translation of theories and concepts of bioethics into the clinical setting. The fourth and final section focuses on academic expressions of bioethics as it is theorised in various disciplines and also as it is taught whether in classrooms or at the patient’s bedside. The book features unique contributions from a range of experts including: Alastair V Campbell; Ruth Chadwick; Angus Dawson; Raymond G. De Vries; Suzanne Ost; Renzo Pegoraro; Rouven Porz; Paul Schotsmans; Jochen Vollmann; Guy Widdershoven and Hub Zwart. Chapter 10 of this book ''You Don't Need Proof When You've Got Instinct!': Gut Feelings and Some Limits to Parental Authority' by Giles Birchley is available under an open access CC BY NC ND license and can be viewed at: http://www. tandfebooks. com/userimages/ContentEditor/1438250845242/9780415737197_chapter10. pdf . | The Voices and Rooms of European Bioethics

GBP 48.99
1

Clinical Cases A Step-by-Step Approach

Clinical Cases A Step-by-Step Approach

It is vitally important for medical students and junior doctors to grasp an understanding of ‘real-life medicine’. This innovative book of cases shows how a particular presentation may progress and the different complications that may arise and emerge over time which may be missed by the ‘snapshot in time' approach taken by many problem-based volumes. The content reflects the average length of stay for a patient in hospital in which their situation can change in a multitude of ways and the management of chronic conditions may also need to be adapted as complications arise. Demonstrates the real bedside experiences that medical students can expect in whichever simple or complex way that they may present Cases selected from a range of sub-specialties for comprehensive coverage across the curriculum Illustrates the complicated progressive problems that will be seen while practicing as a doctor with detailed diagrams and diagnostic imagery to aid understanding Shows with timepoints how differential diagnoses may change as more information becomes available and new symptoms arise Describes a typical initial hospital stay and subsequent presentations to the general practitioner and hospital readmission The Authors Andrew Solomon BM BCH MA(Hons) DM FRCP is a Consultant Physician East and North Hertfordshire NHS Trust Stevenage UK. Julia Anstey BSc (Hons) MBBS is a Foundation Doctor Somerset NHS Foundation Trust Taunton UK. Liora Wittner MBBS BSc is a Resident in Internal Medicine Shamir Medical Centre Be'er Ya'akov Israel. With contributions from Priti Dutta MBBS BSc FRCR Consultant Radiologist Royal Free London NHS Foundation Trust London UK. | Clinical Cases A Step-by-Step Approach

GBP 21.99
1

Learning from Disease in Pets A ‘One Health’ Model for Discovery

Learning from Disease in Pets A ‘One Health’ Model for Discovery

Learning from Disease in Pets: A ‘One Health’ Model for Discovery is the first encompassing reference guide for veterinarians researchers and physicians on conducting studies using spontaneous models of disease in animals. The study of naturally occurring disease in (pet) animals can help model our understanding of the biology prevention and therapy of human and animal diseases. Studies of pet dogs for instance can aid treatment of complex medical problems such as cancer orthopedic cardiopulmonary and neuro-inflammatory diseases and zoonotic infections. Each chapter within this novel cross-species approach is contributed by a leader or leaders in their field of research. Using clinical trials to learn how pets with real diseases respond to therapy can lead to breakthroughs in human medicine as well as benefiting pets suffering from otherwise debilitating illness. Despite similarities of diseases across species there are very few spontaneous models of disease used in research compared with models where disease is induced in healthy laboratory animals. Many medical researchers and veterinarians have a multitude of questions regarding how to use naturally occurring diseases in pets for the discovery of treatments and diagnostics: this book will demonstrate how to safely make this happen. This book encourages veterinarians to build on and disseminate existing findings for the wider benefit of pets and humans. Many pets suffering from incurable illnesses may benefit from clinical trials; the book includes a section on the imperative communication styles necessary within the research environment and with clients a compelling discussion on the ethics of using pets in veterinary clinical research comprehensive tables of diseases that spontaneously occur in animals and humans the regulatory requirements necessary to move therapy from benchside research to patient bedside as well as intricate details on how to design a robust clinical study. | Learning from Disease in Pets A ‘One Health’ Model for Discovery

GBP 82.99
1

Biomedical Photonics Handbook Biomedical Diagnostics

Biomedical Photonics Handbook Biomedical Diagnostics

Shaped by Quantum Theory Technology and the Genomics Revolution The integration of photonics electronics biomaterials and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in medical diagnostics and therapy. The second edition of the Biomedical Photonics Handbook presents fundamental developments as well as important applications of biomedical photonics of interest to scientists engineers manufacturers teachers students and clinical providers. The second volume Biomedical Diagnostics focuses on biomedical diagnostic technologies and their applications from the bench to the bedside. Represents the Collective Work of over 150 Scientists Engineers and Clinicians Designed to display the most recent advances in instrumentation and methods as well as clinical applications in important areas of biomedical photonics to a broad audience this three-volume handbook provides an inclusive forum that serves as an authoritative reference source for a broad audience involved in the research teaching learning and practice of medical technologies. What’s New in This Edition: A wide variety of photonic biochemical sensing technologies have already been developed for clinical monitoring of physiological parameters such as blood pressure blood chemistry pH temperature and the presence of pathological organisms or biochemical species of clinical importance. Advanced photonic detection technologies integrating the latest knowledge of genomics proteomics and metabolomics allow sensing of early disease state biomarkers thus revolutionizing the medicine of the future. Nanobiotechnology has opened new possibilities for detection of biomarkers of disease imaging single molecules and in situ diagnostics at the single cell level. In addition to these state-of-the art advancements the second edition contains new topics and chapters including: • Fiber Optic Probe Design • Laser and Optical Radiation Safety • Photothermal Detection • Multidimensional Fluorescence Imaging • Surface Plasmon Resonance Imaging • Molecular Contrast Optical Coherence Tomography • Multiscale Photoacoustics • Polarized Light for Medical Diagnostics • Quantitative Diffuse Reflectance Imaging • Interferometric Light Scattering • Nonlinear Interferometric Vibrational Imaging • Multimodality Theranostics Nanoplatforms • Nanoscintillator-Based Therapy • SERS Molecular Sentinel Nanoprobes • Plasmonic Coupling Interference Nanoprobes Comprised of three books: Volume I: Fundamentals Devices and Techniques; Volume II: Biomedical Diagnostics; and Volume III: Therapeutics and Advanced Biophotonics this second edition contains eight sections and provides introductory material in each chapter. It also includes an overview of the topic an extensive collection of spectroscopic data and lists of references for further reading. | Biomedical Photonics Handbook Biomedical Diagnostics

GBP 59.99
1