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Metal Toxicology Handbook

Metal Toxicology Handbook

Heavy metals and metalloids singly or in combination induce toxic manifestations either through acute or chronic pathology. In particular long-term chronic exposure to diverse heavy metals and metalloids to humans and animals can lead to numerous physical muscular neurological nephrological and diverse degenerative diseases and dysfunctions including multiple sclerosis muscular dystrophy Parkinson’s and Alzheimer’s diseases cardiovascular disorders and several others. Recognized heavy metals such as lead mercury arsenic cadmium thallium and hexavalent chromium are known for enormous toxicity. The immediate vital signs of acute heavy metal exposure include nausea vomiting diarrhea and acute abdominal pain. Mercury has been identified as the most toxic heavy metal and mercury poisoning is known as acrodynia or pink disease. Similarly lead another toxic heavy metal was at one time an integral part of painting. Metal Toxicology Handbook further explains and discusses the varying attributes of metals discussing toxicity safety and proper human utilization of metals. Beginning with a broad overview of metals metalloids redox biology and neurodegeneration and going further into the roles benefits and toxicity of metals with each section the text contains 28 chapters from eminent researchers and scientists in their respective fields and is a must-have for anyone researching the potential toxicity in metals. Key Features Discusses the pathology of metal toxicity Highlights the benefits of metals Explains the mechanism and salient features of restoring metabolic homeostasis Highlights dose-dependent beneficial and adverse effects of vanadium safety and toxicity The initial introductory section provides a broad overview of metals metalloids redox biology and neurodegeneration. The second section discusses the pathology of metal toxicity in two chapters while the third section highlights the mechanism and salient features of restoring metabolic homeostasis in two chapters. The fourth section demonstrates the aspect of radionuclides toxicity. In a change of pace the fifth section discusses the benefits of metals in four chapters. The sixth section titled Toxic Manifestations by Diverse Heavy Metals and Metalloids provides fourteen chapters that discuss the toxicological mechanism and manifestation of individual metals. The editors have crafted a commentary titled A Treatise on Metal Toxicity and summarized a vivid scenario of metal toxicity and its consequences.

GBP 210.00
1

Polymer Characterization Physical Techniques 2nd Edition

Soil Analysis Handbook of Reference Methods

Introduction to High Performance Computing for Scientists and Engineers

Introduction to High Performance Computing for Scientists and Engineers

Written by high performance computing (HPC) experts Introduction to High Performance Computing for Scientists and Engineers provides a solid introduction to current mainstream computer architecture dominant parallel programming models and useful optimization strategies for scientific HPC. From working in a scientific computing center the authors gained a unique perspective on the requirements and attitudes of users as well as manufacturers of parallel computers. The text first introduces the architecture of modern cache-based microprocessors and discusses their inherent performance limitations before describing general optimization strategies for serial code on cache-based architectures. It next covers shared- and distributed-memory parallel computer architectures and the most relevant network topologies. After discussing parallel computing on a theoretical level the authors show how to avoid or ameliorate typical performance problems connected with OpenMP. They then present cache-coherent non-uniform memory access (ccNUMA) optimization techniques examine distributed-memory parallel programming with message passing interface (MPI) and explain how to write efficient MPI code. The final chapter focuses on hybrid programming with MPI and OpenMP. Users of high performance computers often have no idea what factors limit time to solution and whether it makes sense to think about optimization at all. This book facilitates an intuitive understanding of performance limitations without relying on heavy computer science knowledge. It also prepares readers for studying more advanced literature. Read about the authors' recent honor: Informatics Europe Curriculum Best Practices Award for Parallelism and Concurrency.

GBP 180.00
1

Advanced Rail Geotechnology – Ballasted Track

Advanced Rail Geotechnology – Ballasted Track

Ballast plays a vital role in transmitting and distributing the train wheel loads to the underlying track substructure. The load-bearing capacity safe train speed and the levels of noise and vibration as well as passenger comfort depend on the behaviour of ballast through particle interlocking and the corresponding deformation of this granular assembly. Attrition and breakage of ballast occur progressively under heavy and continual cyclic loading causing track deterioration and rail misalignment affecting safety while exacerbating the intensity of track maintenance. In the absence of realistic computational models the track substructure is traditionally designed using mostly empirical approaches. In this book the authors present the detailed information on the strength deformation and degradation aspects of fresh and recycled ballast under monotonic cyclic and impact loading using innovative geotechnical testing devices. A constitutive model for ballast incorporating particle breakage is presented representing a more realistic stress–strain response. The mathematical formulations and numerical models are validated using controlled experimental simulations and fully instrumented field trials. Revised ballast gradation is described to provide greater track resiliency and extended longevity. The book also provides a detailed description of geosynthetics for substructure improvement considering track deterioration caused by particle degradation fouling and impeded drainage. New to this second edition are extensive discussions on subgrade soil stabilisation causes and mechanisms of soil fluidisation (mud pumping) under cyclic loading and preventive and remedial measures to alleviate undue instability of ballast tracks. This book should prove most beneficial for final-year civil engineering students and for postgraduate teaching and learning. It is an ideal supplement for practising railway engineers and researchers engaged in the challenging tasks of future track design for heavier and faster trains. | Advanced Rail Geotechnology – Ballasted Track

GBP 180.00
1

Biology and Biotechnology of Environmental Stress Tolerance in Plants 3-Volume Set

Biology and Biotechnology of Environmental Stress Tolerance in Plants 3-Volume Set

This new 3-volume set provides a comprehensive understanding of the mechanisms that mediate biosynthesis accumulation and degradation of plant metabolites so as to employ novel strategies to improve crop production and enhance abiotic stress tolerance in plants. Abiotic stresses such as drought high salt cold heat UV radiation heavy metal pollution etc. are increasingly responsible for restricting plant growth and agricultural production and are becoming more alarming due to threats from global climate change. To combat these threats it is imperative to study the underlying mechanisms of stress tolerance from diverse metabolites and the biosynthesis pathways for metabolite production to maintain osmotic balance under diverse environmental stresses. Biology and Biotechnology of Environmental Stress Tolerance in Plants provides that understanding. Volume 1: Secondary Metabolites in Environmental Stress Tolerance focuses exclusively on the diverse secondary metabolites that play a major role in the adaptation of plants to the environment and in overcoming stress conditions as well as their implications in enhancing tolerance mechanisms. The chapters in this section review and integrate the currently available information on the protective role rendered by a wide array of antioxidative secondary metabolites and their regulation during diverse environmental stress. Volume 2: Trace Elements in Environmental Stress Tolerance throws light on the different inorganic trace elements including metal nanoparticles that help to deal with various environmental stresses. While these elements at high level create considerable phytotoxicity and halt metabolic and enzymatic activity they also promote growth and development in limited quantity so that they have significant potential in revamping plant morphology and physiology under stressed conditions. Hence optimum concentration management of these elements can help to mitigate world hunger and contribute toward sustainable agriculture and food security under challenging environments. Volume 3: Sustainable Approaches for Enhancing Environmental Stress Tolerance focuses on the agronomic and biochemical approaches as well as biotechnological and high-throughput technologies including the prospects of genetic engineering epigenetics and the latest CRISPR/Cas technology in generating stress-tolerant plants. The volume provides a clear road map for the implementation of techniques for improving abiotic stress tolerance in plants for better sustenance. Key features: Provides an advanced understanding of the mechanisms of action of secondary metabolites and trace elements in environmental stress tolerance as well as the different agronomic and biotechnological methods that enhances stress tolerance Looks at the overall metabolic pathways and genetic engineering giving a holistic view of plant-level studies of diverse abiotic stresses affecting different metabolic pathways Provides the groundwork to help researchers in designing future programs for identifying novel genes and proteins and targeting proper pathways to develop climate-resilient plants Altogether the three-volume Biology and Biotechnology of Environmental Stress Tolerance in Plants will enhance our understanding of plant responses to environmental stresses and enable implementation of programs and practices that can help us to develop climate-resilient plants with better performance for better yield and quality. | Biology and Biotechnology of Environmental Stress Tolerance in Plants 3-Volume Set

GBP 437.00
1