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The Role of Taste in Kant's Theory of Cognition

Creating Common Ground Connections Healing Divisiveness

The Routledge Companion to Behavioural Accounting Research

A Handbook for Supporting Today's Graduate Students

Bayesian Analysis with R for Drug Development Concepts Algorithms and Case Studies

Bayesian Analysis with R for Drug Development Concepts Algorithms and Case Studies

Drug development is an iterative process. The recent publications of regulatory guidelines further entail a lifecycle approach. Blending data from disparate sources the Bayesian approach provides a flexible framework for drug development. Despite its advantages the uptake of Bayesian methodologies is lagging behind in the field of pharmaceutical development. Written specifically for pharmaceutical practitioners Bayesian Analysis with R for Drug Development: Concepts Algorithms and Case Studies describes a wide range of Bayesian applications to problems throughout pre-clinical clinical and Chemistry Manufacturing and Control (CMC) development. Authored by two seasoned statisticians in the pharmaceutical industry the book provides detailed Bayesian solutions to a broad array of pharmaceutical problems. Features Provides a single source of information on Bayesian statistics for drug development Covers a wide spectrum of pre-clinical clinical and CMC topics Demonstrates proper Bayesian applications using real-life examples Includes easy-to-follow R code with Bayesian Markov Chain Monte Carlo performed in both JAGS and Stan Bayesian software platforms Offers sufficient background for each problem and detailed description of solutions suitable for practitioners with limited Bayesian knowledge Harry Yang Ph. D. is Senior Director and Head of Statistical Sciences at AstraZeneca. He has 24 years of experience across all aspects of drug research and development and extensive global regulatory experiences. He has published 6 statistical books 15 book chapters and over 90 peer-reviewed papers on diverse scientific and statistical subjects including 15 joint statistical works with Dr. Novick. He is a frequent invited speaker at national and international conferences. He also developed statistical courses and conducted training at the FDA and USP as well as Peking University. Steven Novick Ph. D. is Director of Statistical Sciences at AstraZeneca. He has extensively contributed statistical methods to the biopharmaceutical literature. Novick is a skilled Bayesian computer programmer and is frequently invited to speak at conferences having developed and taught courses in several areas including drug-combination analysis and Bayesian methods in clinical areas. Novick served on IPAC-RS and has chaired several national statistical conferences. | Bayesian Analysis with R for Drug Development Concepts Algorithms and Case Studies

GBP 38.99
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Introductory Physics Summaries Examples and Practice Problems

Introductory Physics Summaries Examples and Practice Problems

Physics describes how motion works in everyday life. Clothes washers and rolling pins are undergoing rotational motion. A flying bird uses forces. Tossing a set of keys involves equations that describe motion (kinematics). Two people bumping into each other while cooking in a kitchen involves linear momentum. This textbook covers topics related to units kinematics forces energy momentum circular and rotational motion Newton’s general equation for gravity and simple harmonic motion (things that go back and forth). A math review is also included with a focus on algebra and trigonometry. The goal of this textbook is to present a clear introduction to these topics in small pieces with examples that readers can relate to. Each topic comes with a short summary a fully solved example and practice problems. Full solutions are included for over 400 problems. This book is a very useful study guide for students in introductory physics courses including high school and college students in an algebra-based introductory physics course and even students in an introductory calculus-level course. It can also be used as a standalone textbook in courses where derivations are not emphasized. Key features: Organizes a difficult subject into short and clearly written sections. Can be used alongside any introductory physics textbook. Presents clear examples for every problem type discussed in the textbook. Michael Antosh teaches physics at the University of Rhode Island USA. He obtained a Ph. D. in physics from Brown University. | Introductory Physics Summaries Examples and Practice Problems

GBP 42.99
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Unequal Cities The Challenge of Post-Industrial Transition in Times of Austerity

Unequal Cities The Challenge of Post-Industrial Transition in Times of Austerity

This seminal edited collection examines the impact of austerity and economic crisis on European cities. Whilst on the one hand the struggle for competitiveness has induced many European cities to invest in economic performance and attractiveness on the other national expenditure cuts and dominant neo-liberal paradigms have led many to retrench public intervention aimed at preserving social protection and inclusion. The impact of these transformations on social and spatial inequalities – whether occupational structures housing solutions or working conditions – as well as on urban policy addressing these issues is traced in this exemplary piece of comparative analysis grounded in original research. Unequal Cities links existing theories and debates with newer discussions on the crisis to develop a typology of possible orientations of local government towards economic development and social cohesion. In the process it describes the challenges and tensions facing six large European cities representative of a variety of welfare regimes in Western Europe: Barcelona Copenhagen Lyon Manchester Milan and Munich. It seeks to answer such key questions as:What social groups are most affected by recent urban transformations and what are the social and spatial impacts? What are the main institutional factors influencing how cities have dealt with the challenges facing them? How have local political agendas articulated the issues and what influence is still exerted by national policy? Grounded in an original urban policy analysis of the post-industrial city in Europe the book will appeal to a wide range of social science researchers Ph. D. and graduate students in urban studies social policy sociology human geography European studies and business studies both in Europe and internationally. | Unequal Cities The Challenge of Post-Industrial Transition in Times of Austerity

GBP 39.99
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Using Action Inquiry in Engaged Research An Organizing Guide

Using Action Inquiry in Engaged Research An Organizing Guide

Using Action Inquiry in Engaged Research: An Organizing Guide offers higher education and school professionals practical guidance and methods for using the Action Inquiry Model (AIM) in engaged research initiatives and community partnerships. Replete with group exercises and case studies this guide was originally developed to supplement workshops for faculty administrators and students working on action initiatives that focused on critical educational issues facing local communities. It provides a useful framework and straightforward techniques for building empowering partnerships. The Action Inquiry Model (AIM) includes four stages: • Assessment: Using research and experience to identify critical challenges facing the university with respect to the improvement of educational opportunities• Organization: Developing workgroups to collaborate on initiatives that address critical challenges; providing financial support for new initiatives; and providing release time and professional development opportunities for faculty and staff who engage in reform initiatives• Action Initiatives: Treating reforms as pilot tests for new strategies as a means of promoting organizational learning professional development and student success• Evaluation: Integrating the evaluation of current programs and incorporating new initiatives into the reform process. This guide provides two methods for learning the inquiry process: a step-by-step process for defining tasks for teams of researchers and practitioners working together to use research to inform the educational improvement; and sets of case studies on assessment and action inquiry to inform groups in collectively discussing problems and strategies an approach that supports the classroom use of the Guide. The key tasks in action inquiry initiatives include: 1. Build an understanding of the challenge 2 Identify the causes of the challenge using data to test hypotheses2. Look internally and externally for solutions3. Assess possible solutions4. Develop action plans5. Implement pilot test and evaluateThis guide is appropriate for professional development programs and as a text for higher education Masters and Ph. D. programs. | Using Action Inquiry in Engaged Research An Organizing Guide

GBP 26.99
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Evolution of Government Policy Towards Homosexuality in the US Military The Rise and Fall of DADT

Evolution of Government Policy Towards Homosexuality in the US Military The Rise and Fall of DADT

Throughout history homosexuality has been a complicating factor for men and women electing to serve in the armed forces of the United States. The right to serve became increasingly complicated when the Department of Defense responded to congressional legislation in 1993 by adopting a policy that later became known as don’t ask don’t tell (DADT). DADT permitted homosexual members to serve in the forces so long as they showed no evidence of homosexual behavior. The compromise policy remained in force until Congress passed the Don’t Ask Don’t Tell Repeal Act of 2010 and finally in September 2011 the ban on gay men and lesbians serving openly in the US armed forces officially came to an end. Reflecting on the 20-year period governed by DADT this volume explores the history culture attitudes and impacts of policy evolution from the mid-20th Century through to the present day. It not only provides insight to the scholarly field of how the most powerful institution in the world has viewed and dealt with homosexuality as it transitioned into the 21st century but it is also poised to become a seminal collection for researchers in the decades to come. This book was originally published as a special issue of the Journal of Homosexuality. Parco and Levy have produced a fine edited volume dedicated to deepening our understanding of the federal DADT policy. What has resulted is a deep analysis of the federal policies regarding gays and lesbians in the U. S. military. This volume is filled with rich descriptions and analyses written by the very best thinkers about issues pertaining to gays and lesbians in the U. S. military. Parco and Levy not only offer a comprehensive treatment of DADT but their book will stand the test of time and spur additional important research about gay lesbian bisexual and queer service members. The Rise and Fall of DADT is accessibly written and offers readers a comprehensive understanding of the DADT federal policy and the attendant issues of equity social justice and ever-changing attitudes about LGBTQ people related to the U. S. military and to the larger American society. John P. Elia Ph. D. Editor-in-Chief Journal of Homosexuality and Professor and Associate Chair of Health Education at San Francisco State University USA As Assistant Secretary of Defense for Public Affairs from 2010 to 2012 and the first openly-gay senior official to serve at the Pentagon I was witness to and honored to be an active participant in the historic process that led to the ban on discrimination against lesbian and gay service members: men and women who had been hiding in plain sight while risking their lives to serve their country honorably. In this volume Jim Parco and Dave Levy provide what is perhaps the most comprehensive account to date of the evolution of US government policy regarding LGBT service members. Their study includes outstanding firsthand narratives by many friends who played central roles in the repeal of Don’t Ask/Don’t tell including Sue Fulton Jonathan Lee and former Congressman Patrick Murphy. Parco and Levy provide the opportunity for scholars experts and ordinary citizens from all walks of life to share in those journeys and in the very positive results that were achieved. Douglas B. Wilson former Assistant Secretary of Defense for the United States | Evolution of Government Policy Towards Homosexuality in the US Military The Rise and Fall of DADT

GBP 31.99
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