Molecular Biology Structure and Dynamics of Genomes and Proteomes Molecular Biology: Structure and Dynamics of Genomes and Proteomes second edition illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA RNA and proteins. Emphasis is on the experimental basis of discovery and the most recent advances in the field while presenting a rigorous yet still concise summary of the structural mechanisms of molecular biology. Topics new to this edition include the CRISPR-Cas gene editing system Coronaviruses – structure genome vaccine and drug development and newly recognized mechanisms for transcription termination. The text is written for advanced undergraduate or graduate-level courses in molecular biology. Key Features Highlights the experimental basis of important discoveries in molecular biology Thoroughly updated with new information on gene editing tools viruses and transcription mechanisms termination and antisense Provides learning objectives for each chapter Includes a list of relevant videos from the Internet about the topics covered in the chapter | Molecular Biology Structure and Dynamics of Genomes and Proteomes GBP 64.99 1
Human Molecular Genetics Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics genomics and cell biology. Maintaining the features that have made previous editions so popular this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized coverage of newer DNA sequencing technologies has been expanded and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS functional genomics stem cells and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation. Key features: Fully integrated approach to the molecular aspects of human genetics genomics and cell biology Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms Summary boxes at the end of each chapter provide clear learning points Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study Reorganized into five sections for improved access to related topics Also new to this edition – brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics A proven and popular textbook for upper-level undergraduates and graduate students the new edition of Human Molecular Genetics remains the ‘go-to’ book for those studying human molecular genetics or genomics courses around the world. GBP 74.99 1
Principles of Neurobiology Principles of Neurobiology Second Edition presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations figures in PowerPoint and a Question Bank for adopting instructors. GBP 66.99 1
Strelkauskas' Microbiology A Clinical Approach As with the much-praised prior editions the third edition of Strelkauskas' Microbiology: A Clinical Approach remains a comprehensive introductory textbook written specifically for pre-nursing nursing and allied health students. Clinically relevant throughout it uses the theme of infection as its foundation fitting closely with the 'One Health' approach that is considered increasingly central to the effective control of zoonoses and to combatting antimicrobial resistance. The third edition has been thoroughly revised and updated to reflect the latest developments including the emergence of the SARS-CoV-2 virus and associated COVID-19 pandemic. The book is accompanied by a robust instructor ancillary package that allows educators to incorporate readily the book’s unique approach into their lectures and includes additional materials for students to supplement classroom learning and encourage and support study and self-reflection. Key Features: Student-focused with all elements carefully designed to help students engage with and understand difficult concepts and to spark and hold interest Dedicated learning skill section introduces practical strategies for improving comprehension and retention Numerous text features further support learning and teaching including chapter overviews fast facts case studies and human stories and ‘why is this important?’ highlights A variety of question-and-answer types for self-testing and reflection to support and assess basic learning to challenge students to integrate important concepts and ask students to apply what they have just learned to a specific clinical setting or problem All supported by a comprehensive suite of online resources including lecturer support material and for students interactive questions lecture notes MicroMovies and the BugParade The book is an excellent resource to guide and support inter-professional education in the health sciences and an ideal entry-point to the subject for anyone coming from another discipline and invaluable supplementary reading for medical microbiology and biomedical science students. | Strelkauskas' Microbiology A Clinical Approach GBP 54.99 1
Cellular Signal Processing An Introduction to the Molecular Mechanisms of Signal Transduction Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology biochemistry bioinformatics and pharmacology as well as medical students. The text is organized by three key topics central to signal transduction: the protein network its energy supply and its evolution. It covers all important aspects of cell signaling ranging from prokaryotic signal transduction to neuronal signaling and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes as well as content on new developments in systems biology epigenetics redox signaling and small non-coding RNA signaling. | Cellular Signal Processing An Introduction to the Molecular Mechanisms of Signal Transduction GBP 66.99 1
A First Course in Systems Biology A First Course in Systems Biology is an introduction for advanced undergraduate and graduate students to the growing field of systems biology. Its main focus is the development of computational models and their applications to diverse biological systems. The book begins with the fundamentals of modeling then reviews features of the molecular inventories that bring biological systems to life and discusses case studies that represent some of the frontiers in systems biology and synthetic biology. In this way it provides the reader with a comprehensive background and access to methods for executing standard systems biology tasks understanding the modern literature and launching into specialized courses or projects that address biological questions using theoretical and computational means. New topics in this edition include: default modules for model design limit cycles and chaos parameter estimation in Excel model representations of gene regulation through transcription factors derivation of the Michaelis-Menten rate law from the original conceptual model different types of inhibition hysteresis a model of differentiation system adaptation to persistent signals nonlinear nullclines PBPK models and elementary modes. The format is a combination of instructional text and references to primary literature complemented by sets of small-scale exercises that enable hands-on experience and large-scale often open-ended questions for further reflection. GBP 82.99 1
Biology of Aging Biology of Aging Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging longevity and age-related disease. Intended for undergraduate biology students it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material. Roger McDonald received his Ph. D. from the University of Southern California and is Professor Emeritus in the Department of Nutrition at the University of California Davis. Dr. McDonald’s research focused on mechanisms of cellular aging and the interaction between nutrition and aging. His research addressed two key topics in the field: the relationship between dietary restriction and lifespan and the effect of aging on circadian rhythms and hypothalamic regulation. You can contact Dr. McDonald at rbmcdonald@ucdavis. edu. Related Titles Ahmad S. I. ed. Aging: Exploring a Complex Phenomenon (ISBN 978-1-1381-9697-1) Moody H. R. & J. Sasser. Gerontology: The Basics (ISBN 978-1-1387-7582-4) Timiras P. S. Physiological Basis of Aging and Geriatrics (ISBN 978-0-8493-7305-3) GBP 56.99 1
Plants People and Culture The Science of Ethnobotany Is it possible that plants have shaped the very trajectory of human cultures? Using riveting stories of fieldwork in remote villages two of the world’s leading ethnobotanists argue that our past and our future are deeply intertwined with plants. Creating massive sea craft from plants indigenous shipwrights spurred the navigation of the world’s oceans. Today indigenous agricultural innovations continue to feed clothe and heal the world’s population. One out of four prescription drugs for example were discovered from plants used by traditional healers. Objects as common as baskets for winnowing or wooden boxes to store feathers were ornamented with traditional designs demonstrating the human ability to understand our environment and to perceive the cosmos. Throughout the world the human body has been used as the ultimate canvas for plant-based adornment as well as indelible design using tattoo inks. Plants also garnered religious significance both as offerings to the gods and as a doorway into the other world. Indigenous claims that plants themselves are sacred is leading to a startling reformulation of conservation. The authors argue that conservation goals can best be achieved by learning from rather than opposing indigenous peoples and their beliefs. KEY FEATURES • An engrossing narrative that invites the reader to personally engage with the relationship between plants people and culture • Full-color illustrations throughout—including many original photographs captured by the authors during fieldwork • New to this edition—Plants That Harm a chapter that examines the dangers of poisonous plants and the promise that their study holds for novel treatments for some of our most serious diseases including Alzheimer’s and substance addiction • Additional readings at the end of each chapter to encourage further exploration • Boxed features on selected topics that offer further insight • Provocative questions to facilitate group discussion Designed for the college classroom as well as for lay readers this update of Plants People and Culture entices the reader with firsthand stories of fieldwork spectacular illustrations and a deep respect for both indigenous peoples and the earth’s natural heritage. | Plants People and Culture The Science of Ethnobotany GBP 42.99 1