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Interleukin-2 and Killer Cells in Cancer

Interleukin-2 and Killer Cells in Cancer

This is the first-and only-publication available which provides the most recent information in this particular field of biomedicine. Interleukin-2 (IL-2) and IL-2 activated killer cells have been shown to have a potential in the treatment of a variety of human malignant diseases. This work comprehensively summarizes basic aspects of IL-2 as well as its clinical application therefore making all these aspects easily accessible to the readers. Because of the clinical significance of this molecule in the treatment of cancer the basic and clinical investigations in the IL-2 field are rapidly expanding together with the interest of the scientific and medical community. This book is an excellent educational and teaching tool for scientists clinicians and students. Those who already have expertise in research in the IL-2 area will find this reference indispensible. | Interleukin-2 and Killer Cells in Cancer

GBP 145.00
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Wood Adhesives Chemistry and Technology-Volume 2

Wood Adhesives Chemistry and Technology-Volume 2

The perfect companion to the highly acclaimed Volume 1 of Wood Adhesives Volume 2 presents stimulating discussions on technically and economically importantadhesives for wood bonding-covering their preparation and formulation as well astechniques and suggestions for their application. Like its companion book Wood Adhesives Volume 2 provides up-to-date informationand analysis of new technologies and recent breakthroughs . gives insightinto the relationship between adhesive chemistry and technical application . anddiscusses present and future trends likely to have considerable impact on the field. Elaborating upon general overviews presented in Volume 1 Wood Adhesives Volume 2 includes a chapter on protein adhesives . fills the gap on the chemistryof polyvinyl acetate wood adhesives . contains a detailed discussion of formaldehydeemission . and much more. A complementary and much needed follow-up to Volume 1 Wood Adhesives Volume 2 is essential reading for wood technologists; adhesives and physicalchemists; forest products researchers; polymer scientists; chemical mechanical process and civil engineers who must choose and apply wood adhesives; and advancedundergraduate and graduate students in the above disciplines. | Wood Adhesives Chemistry and Technology-Volume 2

GBP 59.99
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Nutrition and Type 2 Diabetes Etiology and Prevention

Nutrition and Type 2 Diabetes Etiology and Prevention

Over the past two decades type 2 diabetes has emerged as a leading threat to global health and the considerable overlap in obesity and diabetes trends are likely no coincidence. While the underpinnings for both etiologies are linked to lifestyles particularly dietary and physical activity patterns determining optimal approaches for preventing and managing type 2 diabetes using dietary composition remains a challenge. Nutrition and Type 2 Diabetes: Etiology and Prevention rigorously examines various perspectives on diet and type 2 diabetes. The book presents a comprehensive description and evaluation of the central research to date primarily in humans on the macronutrients and their subclasses micronutrients foods beverages and overall dietary patterns with respect to the risk of type 2 diabetes. It addresses the mediating/mechanistic role of obesity and body composition throughout the text where appropriate. The chapter authors all leading researchers in the field discuss fundamental nutritional principles applied to the pathophysiology of type 2 diabetes as well as applied behavioral studies on nutrition and diabetes for each subject area. The depth and breadth of this book includes aspects of the food synergy model for understanding the complicated pathways between nutrition dietary habits and risk for type 2 diabetes. It also examines the effects of artificially sweetened beverages and coffee. This reference provides a review of the science on the potential impact of many components of dietary behavior and nutritional properties on etiology and risk for this disease knowledge that is essential for formulating informed approaches to public health progress in this area. | Nutrition and Type 2 Diabetes Etiology and Prevention

GBP 59.99
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Weed Physiology Volume 2: Herbicide Physiology

Weed Physiology Volume 2: Herbicide Physiology

Volume 2 deals with the mechanisms of herbicide action and of resistance and tolerance to herbicides. The first five chapters of this volume cover the effects of herbicides and adjuvants on the physiology of plants. Professor Black‘s chapter begins by covering the effects of herbicides on photosynthesis including photosynthetic assimilation of nitrogen sulfur and phosphorus. This is followed by Dr. Morelands chapter on herbicide interactions with plant respiration. The third chapter by Professor Bartels deals with the effects of herbicides on chloroplast and cellular development with emphasis on correlating physiological information with ultrasound effects. | Weed Physiology Volume 2: Herbicide Physiology

GBP 170.00
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Revival: Environmental Particles (1993) Volume 2

Revival: Environmental Particles (1993) Volume 2

Environmental Particles Volume 2 presents a critical review of the sampling characterization and behavior of particles in air surface and ground water sediments and solids. The book analyzes the formation aggregation transport and conversion of particles and it evaluates the capabilities of physical and chemical methods of analysis. It also discusses physicochemical properties of environmental particles their spectroscopic characterization and colloid chemical properties and how they affect biochemical and/or toxicological processes. The book will be an important reference for environmental chemists and physicists limnologists oceanographers air and soil scientists analytical chemists environmental engineers and students. | Revival: Environmental Particles (1993) Volume 2

GBP 56.99
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Computational Modelling and Imaging for SARS-CoV-2 and COVID-19

Computational Modelling and Imaging for SARS-CoV-2 and COVID-19

The aim of this book is to present new computational techniques and methodologies for the analysis of the clinical epidemiological and public health aspects of SARS-CoV-2 and COVID-19 pandemic. The book presents the use of soft computing techniques such as machine learning algorithms for analysis of the epidemiological aspects of the SARS-CoV-2. This book clearly explains novel computational image processing algorithms for the detection of COVID-19 lesions in lung CT and X-ray images. It explores various computational methods for computerized analysis of the SARS-CoV-2 infection including severity assessment. The book provides a detailed description of the algorithms which can potentially aid in mass screening of SARS-CoV-2 infected cases. Finally the book also explains the conventional epidemiological models and machine learning techniques for the prediction of the course of the COVID-19 epidemic. It also provides real life examples through case studies. The book is intended for biomedical engineers mathematicians postgraduate students; researchers; medical scientists working on identifying and tracking infectious diseases. | Computational Modelling and Imaging for SARS-CoV-2 and COVID-19

GBP 44.99
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Handbook of Obesity - Volume 2 Clinical Applications

Handbook of Obesity - Volume 2 Clinical Applications

Volume 2 of the 5th Edition of the Handbook of Obesity spotlights on clinical applications for evaluation diagnosis prevention and treatment of obesity. It covers on the several major developments occurred between the previous and the new edition including the effect of SARS-CoV-2 on people with obesity the concept of “Precision Medicine” and new medications approved by USFDA aiding patients with obesity weight loss of 15 to 20%. This volume is structured into 5 parts: Part 1 provides insights from evolution on changes in diet and physical activity and the implications and results for preventing obesity health care costs associated with obesity and the cost-effectiveness of obesity prevention and treatment Part 2 deals with evaluation of overweight patients approaches for classifying obesity and using this knowledge to evaluate patients and addressing ethnic and racial considerations in evaluating patients with obesity Part 3 explains the impact of lifestyle in managing obesity which include behavioural management diet dietary composition and meal timing and the effects of physical activity and exercise in weight loss and weight loss maintenance Part 4 is focused on medications in the management of obesity. This includes drug selection various classes of drugs combination of drugs affecting weight loss effect of herbal agents on weight loss and treatment of obesity in pediatric populations genetic diseases causing obesity and the role of drugs in treating the dyslipidemias Part 5 discusses bariatric surgery its history procedure and effects in details and other surgical techniques including electric stimulation of the vagus nerve gastric balloons intestinal liners and liposuction | Handbook of Obesity - Volume 2 Clinical Applications

GBP 150.00
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Type 2 Diabetes Principles and Practice Second Edition

Type 2 Diabetes Principles and Practice Second Edition

The incidence and prevalence of type 2 diabetes mellitus have increased dramatically in modernized and developing nations over the past few decades. Thoroughly revised and expanded this Second Edition responds to the epidemic and supplies a current overview and guide to the management of diabetes in the modern healthcare environment. This Second Edition offers a current perspective on diabetes demographics epidemiology pathophysiology disease monitoring and approaches to glucose control and supplies new chapters by world-renowned experts on non-pharmacological management options complications of the skin and urogenital function related macrovascular conditions coronary heart disease stroke and peripheral vascular disease and rare forms of diabetes PCOS and NASH. | Type 2 Diabetes Principles and Practice Second Edition

GBP 59.99
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Get Through MRCOG Part 2: MCQs

Get Through MRCOG Part 2: MCQs

Get Through MRCOG Part 2: MCQs covers the breadth and depth of the MRCOG Part 2 examination syllabus and is an essential revision tool for candidates preparing for this examination. The comprehensive and wide collection of practice questions is designed to help the candidate test and assess their knowledge of the subject aiding them in thorough preparation for the exam. The text contains 750 multiple choice stems each with around four associated questions providing the reader with a total of 3000 individual questions with which to test themselves. The material is divided up by subject area allowing candidates to test their knowledge on a particular topic. The 13 'modules' are followed by two mock papers each containing a selection of questions on different subject areas which the reader can attempt under timed conditions. Answers are provided with useful explanatory information for all questions to help the reader understand why their answer is right or wrong. The author Paul Ayuk was clinical lecturer in obstetrics and gynaecology at Oxford University for 6 years and has run an on-line MRCOG course for over 5 years assisting over 8000 candidates worldwide.

GBP 130.00
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Topical Issues of Rational Use of Natural Resources Volume 2

Topical Issues of Rational Use of Natural Resources Volume 2

Topical Issues of Rational Use of Natural Resources 2019 Vol. 2 contains the contributions presented at the XV International Forum-Contest of Students and Young Researchers under the auspices of UNESCO (St. Petersburg Mining University Russia 13-17 May 2019). The Forum-Contest is a great opportunity for young researchers to present their work to the academics involved or interested the area of extraction and processing of natural resources. The topics of the book include: • Geotechnologies of resource extraction: current challenges and prospects • Cutting edge technologies of geological mapping search and prospecting of mineral deposits • Digital and energy saving technologies in mineral resource complex • Breakthrough technologies of integrated processing of mineral hydrocarbon and technogenic raw materials with further production of new generation materials • The latest management and financing solutions for the development of mineral resources sector • Environment protection and sustainable nature management • New approaches to resolving hydrocarbon sector-specific issues Topical Issues of Rational Use of Natural Resources 2019 Vol. 2 collects the best reports presented at the Forum-Contest and is of interest to academics and professionals involved in the extraction and processing of natural resources. | Topical Issues of Rational Use of Natural Resources Volume 2

GBP 44.99
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Design of Prestressed Concrete to Eurocode 2

Design of Prestressed Concrete to Eurocode 2

The design of structures in general and prestressed concrete structures in particular requires considerably more information than is contained in building codes. A sound understanding of structural behaviour at all stages of loading is essential. This textbook presents a detailed description and explanation of the behaviour of prestressed concrete members and structures both at service loads and at ultimate loads and in doing so provide a comprehensive and up-to-date guide to structural design. Much of the text is based on first principles and relies only on the principles of mechanics and the properties of concrete and steel with numerous worked examples. However where the design requirements are code specific this book refers to the provisions of Eurocode 2: Design of Concrete Structures and where possible the notation is the same as in Eurocode 2. A parallel volume is written to the Australian Standard for Concrete Structures AS3600-2009. The text runs from an introduction to the fundamentals to in-depth treatments of more advanced topics in modern prestressed concrete structures. It suits senior undergraduate and graduate students and also practising engineers who want comprehensive introduction to the design of prestressed concrete structures. It retains the clear and concise explanations and the easy-to-read style of the first edition but the content has been extensively re-organised and considerably expanded and updated. New chapters cover design procedures actions and loads; prestressing systems and construction requirements; connections and detailing; and design concepts for prestressed concrete bridges. The topic of serviceability is developed extensively throughout. All the authors have been researching and teaching the behaviour and design of prestressed concrete structures for over thirty-five years and the proposed new edition of the book reflects this wealth of experience. The work has also gained much from Professor Gilbert active and long-time involvement in the development of standards for concrete buildings and concrete bridges. | Design of Prestressed Concrete to Eurocode 2

GBP 35.99
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Current Topics in Nonclinical Drug Development Volume 2

Current Topics in Nonclinical Drug Development Volume 2

The second volume in the CURRENT TOPICS IN NONCLINICAL DRUG DEVELOPMENT SERIES explores the critical issues and current topics in nonclinical drug development. This second volume covers individual topics and strategies in drug development from compound characterization to drug registration. Written by a variety of experts in the field recent and rapid advances in technologies and associated changes in regulatory guidance are discussed. Select topics include: Evolution of Artificial Intelligence (AI) technologies and the impact on toxicologic pathology. Current approaches to carcinogenicity testing. Predicting drug-drug interactions. Current understanding of idiosyncratic drug reaction. Assessing cardiovascular risks beyond QT interval. Use of 3D cell cultures in toxicology and ADME. Development of small molecule-antibody complexes. Differentiating adverse from non-adverse findings in nonclinical studies. Current Topics in Nonclinical Drug Development: Volume 2 will aid toxicologists toxicologic pathologists consultants regulators study directors and nonclinical scientists dealing with day-to-day issues encountered in drug development and assist in formulating strategies for resolution of these issues. In addition the book will be a valuable reference for academicians and graduate students pursuing research related to nonclinical drug development. | Current Topics in Nonclinical Drug Development Volume 2

GBP 170.00
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Complete Revision Guide for MRCOG Part 2 SBAs and EMQs

Complete Revision Guide for MRCOG Part 2 SBAs and EMQs

The examination for Membership of the Royal College of Obstetricians and Gynaecologists(MRCOG) remains one of the most internationally recognised postgraduate examinationsin the specialty. Over the years the examination has evolved in keeping with changes inmedical education; the Part 2 examination now consists of two papers made up of SingleBest Answer (SBA) questions and Extended Matching Questions (EMQ). This invaluable resource consists of 400 SBA questions (200 in Obstetrics and 200in Gynaecology) followed by 400 EMQs (200 in Obstetrics and 200 in Gynaecology) grouped into papers to provide enough material to guide preparations and to give somepractice experience of the examination formats. All the questions have answers withexplanations and sources of evidence. In preparing for the examination candidates shouldmake repeated references to these sources of evidence. There is also general adviceon how to prepare for the examination and discussion of the reasons why trainees failthe examination. | Complete Revision Guide for MRCOG Part 2 SBAs and EMQs

GBP 36.99
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Parallel Computers 2 Architecture Programming and Algorithms

Parallel Computers 2 Architecture Programming and Algorithms

Since the publication of the first edition parallel computing technology has gained considerable momentum. A large proportion of this has come from the improvement in VLSI techniques offering one to two orders of magnitude more devices than previously possible. A second contributing factor in the fast development of the subject is commercialization. The supercomputer is no longer restricted to a few well-established research institutions and large companies. A new computer breed combining the architectural advantages of the supercomputer with the advance of VLSI technology is now available at very attractive prices. A pioneering device in this development is the transputer a VLSI processor specifically designed to operate in large concurrent systems. Parallel Computers 2: Architecture Programming and Algorithms reflects the shift in emphasis of parallel computing and tracks the development of supercomputers in the years since the first edition was published. It looks at large-scale parallelism as found in transputer ensembles. This extensively rewritten second edition includes major new sections on the transputer and the OCCAM language. The book contains specific information on the various types of machines available details of computer architecture and technologies and descriptions of programming languages and algorithms. Aimed at an advanced undergraduate and postgraduate level this handbook is also useful for research workers machine designers and programmers concerned with parallel computers. In addition it will serve as a guide for potential parallel computer users especially in disciplines where large amounts of computer time are regularly used. | Parallel Computers 2 Architecture Programming and Algorithms

GBP 56.99
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Flavonoids and Anti-Aging The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2

Flavonoids and Anti-Aging The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2

The nuclear factor erythroid 2-related factor 2 (Nrf2) was described as a master regulator of the cellular antioxidant response. Moreover many critical biological functions linked to cell viability metabolism autophagy inflammation immunity and differentiation have been attributed to Nrf2 which regulates over 600 genes. It is well known that oxidative stress which Nrf2 can ameliorate plays a key role in many pathologic processes such as aging obesity diabetes cancer and neurodegenerative diseases. Flavonoids on the other hand through their ability to activate and upregulate Nrf2 can have anti-oxidative anti-inflammatory anti-mutagenic and anti-carcinogenic properties. Flavonoids are an essential ingredient in nutraceuticals functional foods and pharmaceuticals. The present book Flavonoids and Anti-Aging: The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2 focuses on the interaction between Nrf2 and flavonoids and their applications in various conditions such as aging osteoporosis cardiovascular diseases and neurodegenerative disease and many other areas. Key Features: Focuses on the mechanisms and use of flavonoids in activating Nrf2 as an anti-aging and WELLNESS molecule Provides a specific approach to flavonoid activation of Nrf2 and its implications in aging and various disease conditions and its applications as nutraceuticals Presents flavonoid-based functional foods Discusses the flavonoid nutraceuticals market and future trends Written by experts in the field this book provides a unique approach to understanding the flavonoid activation of the transcription factor Nrf2 which is responsible for many different disease conditions due to increased reactive oxidative species in the body caused by some physiological triggers. | Flavonoids and Anti-Aging The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2

GBP 150.00
1

Rock Dynamics: Progress and Prospect Volume 2 Proceedings of the Fourth International Conference on Rock Dynamics And Applications (RocDyn

Rock Dynamics: Progress and Prospect Volume 2 Proceedings of the Fourth International Conference on Rock Dynamics And Applications (RocDyn

Rock Dynamics: Progress and Prospect contains 153 scientific and technical papers presented at the Fourth International Conference on Rock Dynamics and Applications (RocDyn-4 Xuzhou China 17-19 August 2022). The two-volume set has 7 sections. Volume 1 includes the first four sections with 6 keynotes and 5 young scholar plenary session papers and contributions on analysis and theoretical development and experimental testing and techniques. Volume 2 contains the remaining three sections with 74 papers on numerical modelling and methods seismic and earthquake engineering and rock excavation and engineering. Rock Dynamics: Progress and Prospect will serve as a reference on developments in rock dynamics scientific research and on rock dynamics engineering applications. The previous volumes in this series (RocDyn-1 RocDyn-2 and RocDyn-3) are also available via CRC Press. | Rock Dynamics: Progress and Prospect Volume 2 Proceedings of the Fourth International Conference on Rock Dynamics And Applications (RocDyn

GBP 150.00
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Building Stones of Milan and Lombardy Volume 2: Stones of Lombardy

Building Stones of Milan and Lombardy Volume 2: Stones of Lombardy

Milan and Lombardy have played an important role in the Italian country since the Roman period. This importance is reflected also by the diffusion of stone architecture: a persisting trait of Milan architecture was the use of different stones in the same building. Milan lies in the middle of the alluvial plain of the Po far from the stone quarries; some waterways were dug out in order to supply the building stones from the surrounding territories. The study of stone as building material was significant at the end of 19th century but then it was largely neglected by both architects and geologists. So it is significant to suggest a study about the stones employed to build in Milan (Volume 1) in relationship with a petrographic study about the features of the stones quarried in the whole Lombard territory (Volume 2). Volume 2 contains the description of the features of the stones reported in Volume 1. These features include metamorphic and magmatic rocks of the Alpine area; sedimentary rocks and loose materials of the Prealpine area; sedimentary rocks of the Apennine area; and loose sediments of the Padania plain. Some stones coming from other northern Italian regions and used in Lombard architecture are also described. Each stone is described in a card containing commercial and historical names petrographic classification macroscopic features mineralogical composition microscopic features geological setting quarry sites transport to yards morphology of dressed elements and surface handworking use in architecture in the whole Lombard territory and abroad and decay morphologies. A particular investigation is addressed to the stones used during the 20th century; a great part of them were never used before in Milan and in Lombardy. | Building Stones of Milan and Lombardy Volume 2: Stones of Lombardy

GBP 110.00
1

Rock Dynamics: Progress and Prospect 2-Volume Set Proceedings of the Fourth International Conference on Rock Dynamics And Applications (Roc

Rock Dynamics: Progress and Prospect 2-Volume Set Proceedings of the Fourth International Conference on Rock Dynamics And Applications (Roc

Rock Dynamics: Progress and Prospect contains 153 scientific and technical papers presented at the Fourth International Conference on Rock Dynamics and Applications (RocDyn-4 Xuzhou China 17-19 August 2022). The two-volume set has 7 sections. Volume 1 includes the first four sections with 6 keynotes and 5 young scholar plenary session papers and contributions on analysis and theoretical development and experimental testing and techniques. Volume 2 contains the remaining three sections with 74 papers on numerical modelling and methods seismic and earthquake engineering and rock excavation and engineering. Rock Dynamics: Progress and Prospect will serve as a reference on developments in rock dynamics scientific research and on rock dynamics engineering applications. The previous volumes in this series (RocDyn-1 RocDyn-2 and RocDyn-3) are also available via CRC Press. | Rock Dynamics: Progress and Prospect 2-Volume Set Proceedings of the Fourth International Conference on Rock Dynamics And Applications (Roc

GBP 280.00
1

Handbook of Conducting Polymers Fourth Edition - 2 Volume Set

Handbook of Conducting Polymers Fourth Edition - 2 Volume Set

In the last 10 years there have been major advances in fundamental understanding and applications and a vast portfolio of new polymer structures with unique and tailored properties was developed. Work moved from a chemical repeat unit structure to one more based on structural control new polymerization methodologies properties processing and applications. The 4th Edition takes this into account and will be completely rewritten and reorganized focusing on spin coating spray coating blade/slot die coating layer-by-layer assembly and fiber spinning methods; property characterizations of redox interfacial electrical and optical phenomena; and commercial applications. | Handbook of Conducting Polymers Fourth Edition - 2 Volume Set

GBP 250.00
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Eleventh International Conference on the Bearing Capacity of Roads Railways and Airfields Volume 2

Eleventh International Conference on the Bearing Capacity of Roads Railways and Airfields Volume 2

Innovations in Road Railway and Airfield Bearing Capacity – Volume 2 comprises the second part of contributions to the 11th International Conference on Bearing Capacity of Roads Railways and Airfields (2022). In anticipation of the event it unveils state-of-the-art information and research on the latest policies traffic loading measurements in-situ measurements and condition surveys functional testing deflection measurement evaluation structural performance prediction for pavements and tracks new construction and rehabilitation design systems frost affected areas drainage and environmental effects reinforcement traditional and recycled materials full scale testing and on case histories of road railways and airfields. This edited work is intended for a global audience of road railway and airfield engineers researchers and consultants as well as building and maintenance companies looking to further upgrade their practices in the field. | Eleventh International Conference on the Bearing Capacity of Roads Railways and Airfields Volume 2

GBP 180.00
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Chemoprophylaxis and Virus Infections of the Respiratory Tract Volume 2

Chemoprophylaxis and Virus Infections of the Respiratory Tract Volume 2

Originally it was our intention to produce a single-volume book covering all aspects and approaches to the problem of specific inhibitors of respiratory viruses. However as the work progressed it became obvious that certain chapters because of the research interests of the authors concentrated particularly on influenza viruses. It seemed logical therefore to divide the book into two volumes the first emphasizing influenza and the second concentrating on other viruses as well as discussing important general aspects of drug screening and clinical testing although the second volume does have some chapters which deal mainly with influenza. | Chemoprophylaxis and Virus Infections of the Respiratory Tract Volume 2

GBP 180.00
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