The Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis - The CAM assay in the study of angiogenesis and metastasis - Do

As pointed out by Auerbach in 1991 ¿Perhaps the most consistent limitation to progress in angiogenesis research has been the availability of simple, reliable, reproducible, quantitative assays of the angiogenesis response.¿ In vitro angiogenesis assays, based on endothelial cell cultures or tissue explant, focus on isolated endothelial cell functions (e.g., endothelial cell proliferation, migration, or invasion) and do not examine the coordination of cell functions required for a successful angiogenic..