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The Future of District Heating - - Bog - Nova Science Publishers Inc - Plusbog.dk

Various Methods and Novel Techniques - Wenli Sun - Bog - Nova Science Publishers Inc - Plusbog.dk

Ototoxicity - - Bog - Nova Science Publishers Inc - Plusbog.dk

Ototoxicity - - Bog - Nova Science Publishers Inc - Plusbog.dk

This compilation focuses on Ototoxicity, the adverse pharmacological reaction affecting the inner ear or auditory nerve, characterised by cochlear or vestibular dysfunction. Although ototoxic medications play an essential role in modern medicine, they can cause harm and lead to significant morbidity. The authors discuss aminoglycoside antibiotics, loop diuretics, platinum-based chemotherapeutic agents, macrolide antibiotics and antimalarial medications which are among the 600 frequently used ototoxic drugs. Next, an overview of cisplatin-associated ototoxicity, namely its clinical features, incidence rates, molecular and cellular mechanisms and risk factors is provided for health care practitioners managing patients with cancer. Ototoxicity and neurotoxicity are defined from the perspective of chemical agents, nicotine and cotinine, that individuals experience through cigarette smoking and environmental tobacco smoke exposure. Mechanisms for toxicity are described by review of animal and human studies revealing changes in peripheral and central auditory structures after exposure to nicotine. The mechanisms of ototoxicity induced by aminoglycoside are also discussed, as well as the usage of these drugs for treatment of several disorders such as Meniere disease, and possible protective agents. In closing, the authors highlight the serious issue of aminoglycoside mediated hearing loss in cystic fibrosis patients, and also discuss alternative approaches for avoiding aminoglycoside-induced cochleotoxicity.

DKK 718.00
1

Networked Control Systems - - Bog - Nova Science Publishers Inc - Plusbog.dk

Networked Control Systems - - Bog - Nova Science Publishers Inc - Plusbog.dk

Networked Control System (NCS) can be regarded as a special type of control system in which sensors, controllers and actuators are connected to a closed loop. Media-sharing characteristics, time-delay, data packet dropout and data displacement are inevitable phenomena in such a control system, which can greatly degrade the control performance, and even make the control system unstable. Alleviating these effects has become one of the most attractive research hotspots in the last two decades. All the above three problems can be summarized as the time-delay issue. There are two kinds of time-delay compensation strategies: one is active compensation, and the other is passive compensation. For the former, prediction is the core idea. Selecting the appropriate candidate predicted control action according to the time delay information is a feasible solution. For the latter, making the system insensitive to delay is a good choice. This book covers the design, modeling, control, simulation and application of the networked control system. This book addresses some original contributions reporting the latest advances in networked control. It aims to gather the latest research on state-of-the-art methods, simulations and applications of networked control techniques. The editor hopes it can reveal some tendencies in this research field and benefit readers including professional researchers and students. This is an interesting collection of networked control techniques, such as date-based control, tracking control, event-triggered control, formation control, etc.

DKK 718.00
1